The aim of this work is to prepare I-NR using a photodegradation method, hence to characterize its physical and chemical properties. In this study, UV light was used to degrade NR in latex state. Reaction parameters such as UV radiation, temperature, hydrogen peroxide, reaction time, DRC and stabilizers showed synergistic effect and influenced the reaction's efficiency. At an optimum reaction condition, the molecular weight of NR was reduced from 544 x 103 g/mol to about 18 x 103 g/mol with almost negligible amount of gel content. The zeta potential of NR latex was increased during the photodegradation, provided by the negatively charge of fatty acid. Dispersed the Ti02 in latex showed catalytic effect on the photodegradation reaction when the molecular weight of LNR was further reduced to about 7 x 103 g/mol with negligible amount of gel content. The molecular structure of LNRs were similar to that the NR, but with increasing of hydroxyl and carbonyl groups on its chain. These functional groups were formed as a result of chain cleavage and located at the chain end.